ABSTRACT
Background: There is no information about the prevalence of thyroidal diseases in the general Chilean population. Aim: To assess the prevalence of thyroidal diseases in individuals attended in occupational health examinations. Subjects and methods : Four hundred seventy two individuals were examined between 1998 and 1999. In all, serum levels of thyroid hormones, TSH and anti thyroidal antibodies (anti microsomal, anti thyroid peroxidase and anti thyroglobulin) were measured. Results: Forty four subjects were excluded from the study due to an incomplete medical record and 18 due to a personal history of thyroidal disease. Abnormal serum levels of thyroid hormones or TSH were detected in 28 subjects (6.8 percent). Four (1 percent) had hypothyroidism, 23 a subclinical hypothyroidism (5.6 percent) and one (0.2 percent) had hyperthyroidism. In 87 subjects (21.2 percent) at least one of the antibodies was positive. Positive anti thyroid antibodies were found in 14 of 28 subjects (50 percent) with abnormal thyroid hormone levels, compared with 73 of 382 subjects (19.1 percent) with normal thyroid hormone levels. Thyroid dysfunction was twice as frequent in women than in men. Conclusions: In this sample, a 6.8 percent prevalence of abnormal thyroid function tests was detected
Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Thyroid Diseases/epidemiology , Occupational Health/statistics & numerical data , Antibodies/blood , Thyroid Function TestsABSTRACT
In two females aged 27 and 32 years old, an aggravation of their panic disorder coincided with the appearance of clinical signs of hyperthyroidism. The clinical diagnosis was confirmed with the finding of raised thyroid hormone levels and undetectable TSH levels. These two cases highlight the importance of routine thyroid function assessment in patients with panic disorder, mainly in those with partial response to medications or when symptoms aggravate, despite an adequate treatment
Subject(s)
Humans , Female , Adult , Hyperthyroidism/complications , Panic Disorder/complications , Propylthiouracil/therapeutic use , Citalopram/therapeutic use , Clonazepam/therapeutic use , Iodine Radioisotopes/therapeutic use , Thyroid Function TestsABSTRACT
Se aplicó una pauta de detección de hijo no deseado (HND) en 556 puérperas de un hospital urbano de la ciudad de Santiago, durante el mes de diciembre de 1987. Esta pauta contempló 10 criterios de selección, a los cuales se les asignó un puntaje empírico de acuerdo a su importancia relativa. Al sumar el puntaje de cada ítem, la población estudiada quedó clasificada en 3 grupos: HND, deseados (HD) o dudosos. Los HND alcanzaron a 4,5% (n=25), 4,1% los dudosos (n=23) y 91,4% (n=508) los niños deseados. Al comparar las características de los HND con las de los HD se observó que los primeros se distribuyen en madres con menor educación, mala relación de pareja, antecedentes de 3 o más partos previos e inicio tardío del control de embarazos (significativo). No se aprecian diferencias de importancia al analizar la edad de las madres, ni al estudiar algunas características socioeconómicas de ambos grupos. Llama la atención el porcentaje de ilegitimidad (37,6%) que se encontró en la muestra estudiada. Se discute la aplicabilidad del instrumento de detección y la importancia de la investigación de este problema, con el fin de conocer la historias natural del HND, factores condicionantes y mecanismos de prevención